Karam was playing Cellblock in the Citadel dungeons, and was playing Number 5. The Lupe began to rant about Jelly World, and knocked all the pieces off the board. Master Vex refused to let Karam leave until he finished the game - and although many months went past, Karam wasn't able to finish a game against Number 5. The time spent with the Lupe sent Karam mad as well, and he now rants about Jelly World.
From the picture with the story, it appears that Karam is a blue Xweetok. He appeared in issue #21.