This adventure told the tale of Rohane and his crew of Neopets, as their ship was infested with a computer virus. Locked on a course to the sun, the crew had to enter the computer simulations of five different lands in order to defeat the virus. We have a different hub for generic monsters encountered during the game.
Most of NeoQuest II takes place inside the computer simulation, therefore most of the characters that only appear in NeoQuest II may not exist on the actual Neopia. The exceptions to this are Rohane, Mipsy, Talinia and Velm, the members of the ship's crew. Phebiya has also been confirmed to exist.